LANGEBIO Cinvestav, Mexico

Andrés Moreno Estrada

Principal Investigator | | Twitter | Scholar

Andres I am a medical doctor and population geneticist deeply interested in molecular evolution and its implications in human population history and medical genomics. During my PhD I was trained in evolutionary and population genetics, which complemented my previous medical background. As a postdoctoral fellow with Dr. Carlos Bustamante and research associate at Stanford University, my work integrated genomics, evolution and precision medicine in many different projects involving large collections of populations, in particular from the Americas and the Pacific. Our group is interested in human evolution, adaptation, and population history as well as the biomedical implications of human genetic diversity in underserved populations of the world.

Adriana Garmendia

Laboratory Administrator and Project Manager |

Adriana I am the academic and administrative assistant of the Lab. I got my masters degree in Landscape Ecology at the Ecosystems Research Institute and Sustainability, UNAM. Although I love science I think it only reaches out to few people, especially in Mexico; that’s why my new passion is science communication. I like hiking, nature photography and I am a tea lover.

Mashaal Sohail

Postdoctoral Fellow | | Academia | Scholar | Twitter

Mashaal I am a human geneticist interested in human history and evolution. I received my bachelor’s degree from MIT in biological engineering and attended graduate school at Harvard University where I received a PhD in systems biology and a master’s degree in history of science. My scientific interests lie across theoretical and applied questions in population genetics. For my PhD thesis in Shamil Sunyaev’s lab, I focused on genomic analyses to tackle theoretical problems in population genetics particularly relating to natural selection. Some questions I have worked on include the relationship of allelic age to mono-allelic gene expression, how humans tolerate the “mutation load” due to incoming deleterious mutations through genome-wide synergistic epistasis, and how polygenic adaptation signals on human height using existing GWAS are confounded by population structure. In my post-doc, I will be working with Andres Moreno Estrada and an international team on the Mexico Biobank where I will be leading the population genetics analyses of 6000 genotyped individuals from across Mexico. I am also passionate about science communication, history and philosophy of science, and the intersection of science and art. I love traveling and experiencing different cultures and foods..

Consuelo Quinto

Postdoctoral Fellow |

Consuelo I am a graduate of the Undergraduate Program on Genomic Sciences from the National Autonomous University of Mexico, and obtained my PhD degree from the Graduate Interdisciplinary Program in Genetics at the University of Arizona. The focus of my dissertation was the use of SNP array data to infer the demographic history of human admixed populations. I am involved in different projects at the Moreno Lab including the demographic study of Near and Remote Oceania and the ancestry service at LANGEBIO. My interests are human evolution, population and forensic genetics. I love Star Wars.

Sergio Nigenda

Postdoctoral Fellow | | Website | Twitter

Nigenda I am a marine biologist graduated from the Universidad Autonoma de Baja California Sur (UABCS) in La Paz, Mexico, and obtained my doctoral degree from the Department of Ecology and Evolutionary Biology at the University of California, Los Angeles (UCLA). My research interests have mainly focused on evolutionary biology of non-model mammal species (i.e. whales, marsupials and coatis) with an emphasis in ecological and evolutionary genomics, phylogeography, phenotypic diversity associated to patterns of gene expression and adaptation to different environments. In the Moreno lab I am involved in several projects, including fin whale, Virginia opossum and sea otter population genomics, and in collaboration with María Avila from LIIGH-UNAM we are exploring genetic variants related to skin pigmentation that might be under selection in human afro-mexican populations. I like hiking, camping, swimming and surfing.

Alex Ioannidis

Postdoctoral Fellow

Alex Alex is also a Postdoctoral Research Fellow at Stanford's Biomedical Data Sciences Department. He graduated from Harvard in Chemistry and Physics and earned an M.Phil in Computational Biology and Diploma in Greek from the University of Cambridge. He has a Ph.D. in Computational and Mathematical Engineering from Stanford, where he teaches machine learning and data science. Prior to Stanford, he worked in superconducting computing research at Northrop Grumman. His work focuses on applying computational methods to problems in human genetics and population history. He is an integral part of the Moreno Lab, advising in the application and development of ancestry-specific methods for the deconvolution of complex demographic patterns.

Aaron Ragsdale

Postdoctoral Fellow |

Aaron I am a population geneticist interested in the demographic and selective processes that shape organismal variation. I received my PhD from the Program in Applied Mathematics and the University of Arizona, and I recently finished a three year postdoc at McGill University’s Department of Human Genetics. My research combines the development of evolutionary theory, computational approaches, simulations, and application to large-scale sequencing datasets to make inferences about evolutionary and demographic history from data. My recent work has focused on predicting and measuring patterns of linkage disequilibrium, which is used to infer demographic history in multi-population models, and I am particularly interested in learning about human origins and deep population structure in human history. Outside of work, I enjoy a game of chess, some hiking and backpacking, and growing a garden.

Andrés Jiménez Kaufmann

Masters Student |

caca I am a graduate of the Undergraduate Program on Genomic Sciences from the National Autonomous University of Mexico (UNAM). I'm currently working in the genetics of complex traits in admixed populations. My project involves both theoretical and applied approaches. For the applied part I'm creating an imputation reference panel that better represents the genetic variation of native American populations so we can increase the statistical power of genetic associations. I'm also involved in investigating the genetic basis of the immune response to a set of common pathogens in Mexico.

María José Palma

Masters Student |

majo I am a graduate of the Undergraduate Program on Genomic Sciences from the National Autonomous University of Mexico (UNAM). I am currently a master's student from the Integrative Biology program at CINVESTAV. The main subject of my project is the description of the sex-specific history of the Mexican population through the analysis of the MXBioBank data.

Daniela Orozco

Masters Student |

dani Daniela is an M.Sc. student at CINVESTAV and alumna of the Undergraduate Program on Genomic Sciences from the National Autonomous University of Mexico (UNAM). She's currently working with ancient DNA from the archaeological site Cañada de la Virgen, using whole-genome sequencing and reference panels from different populations. Daniela is also involved in the Afro-Caribbean project, which combines genomics and molecular approaches to study demographic events like migration and admixture. She's also interested in the bioethics related to genomic population field. When not in the lab, she enjoys baking and reading (novels and tweets mainly).

Carmina Barberena

Masters Student |

dani I'm (also) a graduate of the Undergraduate Program on Genomic Sciences from the National Autonomous University of Mexico (UNAM). My current project in MorenoLab involves the analysis of identity-by-descent genomic segments to determine the population structure of Mexico and their implications in biomedical traits using the data from the Mexican BioBank. I am also involved in other projects as the Oceanian Genome Variation Project. I like photography, surrealist paintings, and good-looking cocktails, I also love rats; one of my dreams is to have a pet rat named Bojack.

Pablo Guevara

PhD Student |

pablo I am an experimental biologist from University of Guanajuato. I got a masters degree at CICESE working with molecular ecology analyses focused on population structure, phylogeography and selections signals of a reef fish distributed from California to Ecuador. Nowadays I will focus research on demographic history and genetic load analyses from full-genome assemblies of fin whales (Balaenoptera physalus). I love traveling, camping, swimming and teaching science to younger scientists wherever they can be found! Social geek and Arcade-games lover.

Sofía Vieyra

Student Intern |

sofía I am an undergrad student of the program of Genomic Sciences offered by National Autonomous University of Mexico (UNAM). The project I am currently working on in the lab is the demographic study of the populations in Oceania. I am interested in population genetics, evolution, and domestication.

Fernanda Renee

Student Intern

fernanda I am a junior student of the Undergraduate Program on Genomic Sciences from the National Autonomous University of Mexico (UNAM). My current project consists of detecting genes that may be under positive selection in the Virginia opossum, causing differences in size and skin pigmentation across populations in North America. I´m interested in immunology, and population and evolutionary genomics. I enjoy coding, petting dogs, going to the beach and (occasional) jogging.

Emiliano Rodriguez

Student Intern

emiliano I'm an undergraduate student of the Program on Genomic Sciences at the National Autonomous University of Mexico (UNAM). Currently, I'm part of the Non-Model Organism Project at MorenoLab, which involves demographic and population structure studies in opossum SNPs. I'm also interested inevolutionary and population genomics, modern history and cinema.


Lab's Pet 🐶 | Instagram

Alex Female Tricolor Welsh Corgi Pembroke, official pet of this lab. I have a graduate degree in chewing stuff and stealing socks, a masters in making people smile. My current position involves cheering-up all the lab members and make their academic life less stressful. Love ice-cubes, long walks and making new friends (furry or not).

Former Lab Members

  • Javier Blanco-Portillo (Masters Student) | Twitter | Scholar | Current Lab
  • Juan Esteban Rodríguez (Masters Student) | Twitter
  • Mitzi Flores (MX Biobank Project Manager)
  • Pavel Salazar (Masters Student)
  • Erika Landa (Masters Student)
  • Patricio Pezo (Visiting PhD Student)
  • Eduardo González (Undergraduate Student)

  • Collaborators

  • Karla Sandoval (LANGEBIO-CINVESTAV)
  • Selene Fernández Valverde (LANGEBIO-CINVESTAV)
  • María Ávila Arcos (LIIGH)
  • Diego Cortez (UNAM)
  • Samuel Canizales (UNAM)
  • Carlos Bustamante (Stanford University)
  • Mark Stoneking (Max Planck Institute for Evolutionary Anthropology)
  • Martin Sikora (Centre for GeoGenetics)
  • Elena Bosch (Institut de Biologia Evolutiva Barcelona)
  • David Comas (Institut de Biologia Evolutiva Barcelona)
  • Guido Barbujani (University of Ferrara)
  • John Novembre (University of Chicago)
  • Simon Gravel (McGill University)
  • Eimear Kenny (Mount Sinai)
  • Anne Stone (Arizona State University)
  • Mauricio Moraga (Universidad de Chile)
  • Ricardo Verdugo (Universidad de Chile)
  • Sandra Romero (INMEGEN)
  • Víctor Acuña (ENAH)
  • Lourdes García-García (INSP)
  • Teresa Tusie-Luna (INCMNSZ)
  • Carla Gallo (Universidad Peruana Cayetano Heredia)