Publications

Year Authors Journal Title Link
2026 Barberena-Jonas C, Medina-Muñoz SG, Cedillo-Castelán V,..., Moreno-Estrada A Nature Medicine Clinical genetic variation across Hispanic populations in the Mexican Biobank DOI
2025 Espinosa-Jaime A, Zambada-Moreno O, Corona-Gomez JA,..., Moreno-Estrada A and Ortiz-Ramírez C bioRxiv SiteCELL enables on-site PBMCs purification and cryopreservation for immune single cell profiling of diverse ancestries DOI
2025 Taylor K,..., Moreno-Estrada A, et al. medRxiv Improving type 2 diabetes polygenic risk scores by incorporating rare, low-frequency, and population-specific variants DOI
2025 Struck TJ,..., Moreno-Estrada A, et al. Mol Biol Evol GHIST 2024: The First Genomic History Inference Strategies Tournament DOI
2025 Possik PA,..., Moreno-Estrada A, et al. Cell Exploring Latin America one cell at a time DOI
2025 Barberena-Jonas C,..., Moreno-Estrada A, et al. Genes & Diseases Genetic analysis of APOE reveals distinct origins and distribution of ancestry-enrichment haplotypes in the Mexican Biobank DOI
2025 Struck TJ,..., Moreno-Estrada A, et al. bioRxiv GHIST 2024: The 1st Genomic History Inference Strategies Tournament DOI
2025 Huerta-Chagoya A,..., Moreno-Estrada A, et al. medRxiv Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries DOI
2025 Lin M,..., Nigenda-Morales SF, Beichman AC,Nuñez-Valencia PG,..., Moreno-Estrada A, et al. bioRxiv The distribution of fitness effects varies phylogenetically across animals DOI
2025 Gusareva ES,..., Moreno-Estrada A, et al. Science From North Asia to South America: Tracing the longest human migration through genomic sequencing DOI
2025 Yang Z,..., Moreno-Estrada A, Sohail M, et al. Am J Hum Genet Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies DOI
2025 Schwartz-Marin E,..., Moreno-Estrada A, et al. Front Genet Genetic ancestry and the colonial legacies of race in genomics: a cross-disciplinary dialogue DOI
2024 Loh L,..., Barberena-Jonas C, Oceanian Genome Variation Project Consortium, Moreno-Estrada A, et al. Cell An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania DOI
2024 González-Buenfil R, Vieyra-Sánchez S, Quinto-Cortés CD,...,Barberena-Jonas C,..., Moreno-Estrada A. Genome Biol Evol Genetic Signatures of Positive Selection in Human Populations Adapted to High Altitude in Papua New Guinea DOI
2024 Sohail M & Moreno-Estrada A Dis Model Mech The Mexican Biobank Project promotes genetic discovery, inclusive science and local capacity building DOI
2024 Chong AY, Brenner N, Jimenez-Kaufmann A,..., Moreno-Estrada A, et al. Am J Hum Genet A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy DOI
2023 Sohail M, Palma-Martínez MJ, Chong AY, Quinto-Cortés CD, Barberena-Jonas C, Medina-Muñoz SG, Ragsdale A,..., Moreno-Estrada A. Nature Mexican Biobank advances population and medical genomics of diverse ancestries DOI
2023 Beichman AC, Robinson J, Lin M, Moreno-Estrada A, Nigenda-Morales S, Harris K Mol Biol Evol Evolution of the Mutation Spectrum Across a Mammalian Phylogeny DOI
2023 Medina-Muñoz SG,..., Moreno-Estrada A, Ragsdale AP. Am J Hum Genet Demographic modeling of admixed Latin American populations from whole genomes DOI
2023 Nigenda-Morales SF, Lin M,Nuñez-Valencia PG,..., Ragsdale AP,..., Moreno-Estrada A, et al. Nat Commun The genomic footprint of whaling and isolation in fin whale populations DOI
2023 Beichman AC, Robinson J, Lin M, Moreno-Estrada A, Nigenda-Morales S, Harris K bioRxiv "Evolution of the mutation spectrum across a mammalian phylogeny" DOI
2023 Villa-Islas V,..., Rodríguez-Rodríguez JE,..., Sandoval K, Nieves-Colón MA,..., Moreno-Estrada A, et al. Science Demographic history and genetic structure in pre-Hispanic Central Mexico DOI
2023 Huerta-Chagoya A,..., Moreno-Estrada A; Mexican Biobank; Aguilar-Salinas CA, et al. Diabetologia The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes DOI
2023 Beichman AC,..., Moreno-Estrada A, et al. Mol Ecol Genomic analyses reveal range-wide devastation of sea otter populations DOI
2022 Caro-Consuegra R, Nieves-Colón MA,..., Sandoval K, Moreno-Estrada A, et al. Mol Biol Evol Uncovering Signals of Positive Selection in Peruvian Populations from Three Ecological Regions DOI
2022 Liu YC,..., Quinto-Cortés CD,..., Moreno-Estrada A, et al. Science Ancient DNA reveals five streams of migration into Micronesia and matrilocality in early Pacific seafarers DOI
2022 Nieves-Colón MA, Badillo Rivera KM, Sandoval K,..., González-Buenfil R,...,Moreno-Estrada A. Am J Hum Genet Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes DOI
2022 Mendoza-Revilla J,...,Nieves-Colón MA,..., Moreno-Estrada A, et al. Mol Biol Evol Disentangling Signatures of Selection Before and After European Colonization in Latin Americans DOI
2022 Bastard P,..., Sandoval K, Barberena-Jonas C, Quinto-Cortés CD,..., Moreno-Estrada A, et al. J Exp Med A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes DOI
2022 Rodríguez-Rodríguez JE, Ioannidis AG, Medina-Muñoz SG, Barberena-Jonas C, Blanco-Portillo J, Quinto-Cortés CD, Moreno-Estrada A. Philos Trans R Soc Lond B Biol Sci The genetic legacy of the Manila galleon trade in Mexico DOI
2022 Jiménez-Kaufmann A, Chong AY, Cortés A, Quinto-Cortés CD,..., Medina-Muñoz SG, Sohail M, Palma-Martinez MJ,..., Moreno-Estrada A. Front Genet Imputation Performance in Latin American Populations: Improving Rare Variants Representation With the Inclusion of Native American Genomes DOI
2022 Ojeda-Granados C,..., Jiménez-Kaufmann A,..., Moreno-Estrada A, et al. Mol Biol Evol Dietary, Cultural, and Pathogens-Related Selective Pressures Shaped Differential Adaptive Evolution among Native Mexican Populations DOI
2021 Ongaro L,..., Moreno-Estrada A, et al. Genes (Basel) Evaluating the Impact of Sex-Biased Genetic Admixture in the Americas through the Analysis of Haplotype Data DOI
2021 Ioannidis AG, Blanco-Portillo J, Sandoval K, Hagelberg E, Barberena-Jonas C, Hill AVS, Rodríguez-Rodríguez JE,..., Quinto-Cortés CD,..., Moreno-Estrada A. Nature Paths and timings of the peopling of Polynesia inferred from genomic networks DOI
2021 Ongaro L,..., Moreno-Estrada A, et al. Hum Mol Genet Continental-scale genomic analysis suggests shared post-admixture adaptation in the Americas DOI
2020 Bravo-Lopez M,..., Moreno-Estrada A, Nieves-Colón MA,..., Sandoval K, et al. Philos Trans R Soc Lond B Biol Sci Paleogenomic insights into the red complex bacteria Tannerella forsythia in Pre-Hispanic and Colonial individuals from Mexico DOI
2020 Ioannidis AG, Blanco-Portillo J, Sandoval K,..., Rodríguez-Rodríguez JE, Quinto-Cortés CD,..., Moreno-Estrada A. Nature Native American gene flow into Polynesia predating Easter Island settlement DOI
2020 Verdugo RA,..., Moreno-Estrada A,..., Sandoval K, et al. Biol Res Development of a small panel of SNPs to infer ancestry in Chileans that distinguishes Aymara and Mapuche components DOI
2020 Ávila-Arcos MC, McManus KF, Sandoval K, Rodríguez-Rodríguez JE,...,Moreno-Estrada A. Mol Biol Evol Population History and Gene Divergence in Native Mexicans Inferred from 76 Human Exomes DOI
2019 Ongaro L,..., Moreno-Estrada A, et al. Curr Biol The Genomic Impact of European Colonization of the Americas DOI
2019 Wojcik GL,..., Moreno-Estrada A,..., Sandoval K, et al. Nature Genetic analyses of diverse populations improves discovery for complex traits DOI
2019 Huerta-Chagoya A,..., Salazar-Fernandez EP,Moreno-Estrada A, et al. BMC Genet A panel of 32 AIMs suitable for population stratification correction and global ancestry estimation in Mexican mestizos DOI
2019 Spear ML,..., Sandoval K, et al. Pharmacogenomics J A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma DOI
2019 Gignoux CR,..., Moreno-Estrada A, Sandoval K, et al. J Allergy Clin Immunol An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos DOI
2018 Belbin GM, Nieves-Colón MA, Kenny EE, Moreno-Estrada A, Gignoux CR Curr Opin Genet Dev Genetic diversity in populations across Latin America: implications for population and medical genetic studies DOI
2018 de la Fuente C,..., Moreno-Estrada A, et al. Proc Natl Acad Sci U S A Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia DOI
2018 Mak ACY,..., Moreno-Estrada A, Sandoval K, et al. Am J Respir Crit Care Med Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma DOI
2016 Alarcón-Riquelme ME,..., Moreno-Estrada A, et al. Arthritis Rheumatol Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture DOI
2016 Mallick S,..., Moreno-Estrada A, et al. Nature The Simons Genome Diversity Project: 300 genomes from 142 diverse populations DOI
2015 Arteaga MC,..., Moreno-Estrada A, et al. Genom Data Genomic variation in recently collected maize landraces from Mexico DOI
2015 Homburger JR, Moreno-Estrada A, et al. PLoS Genet Genomic Insights into the Ancestry and Demographic History of South America DOI
2015 Raghavan M,..., Moreno-Estrada A, et al. Science POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans DOI
2015 Pino-Yanes M,..., Moreno-Estrada A, Sandoval K, et al. J Allergy Clin Immunol Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos DOI
2015 Pino-Yanes M,..., Moreno-Estrada A, Sandoval K, et al. J Allergy Clin Immunol Genetic ancestry influences asthma susceptibility and lung function among Latinos DOI
2014 Moreno-Estrada A,..., Sandoval K, et al. Science Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits DOI
2014 Sikora M,..., Moreno-Estrada A, et al. PLoS Genet Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe DOI
2014 Galanter JM,...,Moreno-Estrada A,Sandoval K, et al. J Allergy Clin Immunol Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study DOI
2014 Drake KA,...,Moreno-Estrada A, Sandoval K, et al. J Allergy Clin Immunol A genome-wide association study of bronchodilator response in Latinos implicates rare variants DOI
2013 Carpenter ML,..., Sandoval K, Moreno-Estrada A, et al. Am J Hum Genet Pulling out the 1%: whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries DOI
2013 Gravel S,..., Moreno-Estrada A, Sandoval K, et al. PLoS Genet Reconstructing Native American migrations from whole-genome and whole-exome data DOI
2013 Moreno-Estrada A,...,Sandoval K, et al. PLoS Genet Reconstructing the population genetic history of the Caribbean DOI
2013 Kumar R,..., Moreno-Estrada A, Sandoval K, et al. J Allergy Clin Immunol Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: the Genes-environments and Admixture in Latino Asthmatics (GALA II) study DOI
2012 Kidd JM,..., Moreno-Estrada A, et al. Am J Hum Genet Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation DOI
2012 Antolin MF,..., Moreno-Estrada A, et al. Evolution Evolution and medicine in undergraduate education: a prescription for all biology students DOI
2012 Sandoval K, Moreno-Estrada A, et al. Am J Phys Anthropol Y-chromosome diversity in Native Mexicans reveals continental transition of genetic structure in the Americas DOI
2012 Kenny EE,..., Moreno-Estrada A, et al. Science Melanesian blond hair is caused by an amino acid change in TYRP1 DOI
2012 Chen R,..., Moreno-Estrada A, et al. PLoS Genet Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases DOI
2012 Keller A,..., Moreno-Estrada A, et al. Nat Commun New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing DOI
2012 Henn BM,..., Moreno-Estrada A, et al. PLoS Genet Genomic ancestry of North Africans supports back-to-Africa migrations DOI
2010 Henn BM, Gravel S, Moreno-Estrada A, Acevedo-Acevedo S, Bustamante CD Hum Mol Genet Fine-scale population structure and the era of next-generation sequencing DOI
2010 Moreno-Estrada A,..., et al. BMC Evol Biol African signatures of recent positive selection in human FOXI1 DOI
2010 Bryc K,..., Moreno-Estrada A, et al. Proc Natl Acad Sci U S A Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations DOI
2010 Acuña-Alonzo V,..., Moreno-Estrada A, et al. Hum Mol Genet A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans DOI
2009 Bosch E,..., Moreno-Estrada A, et al. BMC Genomics Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD DOI
2009 Moreno-Estrada A,..., et al. Mol Biol Evol Interrogating 11 fast-evolving genes for signatures of recent positive selection in worldwide human populations DOI
2008 Morcillo-Suarez C,..., Moreno-Estrada A, et al. Bioinformatics SNP analysis to results (SNPator): a web-based environment oriented to statistical genomics analyses upon SNP data DOI
2008 Moreno-Estrada A,..., et al. Mol Biol Evol Signatures of selection in the human olfactory receptor OR5I1 gene DOI